Knee Replacement Surgery Cost in South Carolina (2026)
Modest savings vs. the US average · SC
What Drives Pricing Here
Three factors explain most of why knee replacement surgery costs what it does in South Carolina.
Regional Price Parity
South Carolina's cost-of-living index sits at 93.5 — meaningfully below the national benchmark (100). This directly scales facility and staffing overhead, which flow through to every procedure price.
Specialist Availability
71 facilities perform this procedure in South Carolina — competition keeps pricing honest and gives you real leverage to shop quotes.
Vs. National Benchmark
At -6.5% below the national average ($35,000), South Carolina is a discount market. Often driven by lower overhead or less metro concentration — quality can still be excellent.
Knee Replacement Surgery in South Carolina: What to Know
South Carolina offers diverse options for knee replacement. Prisma Health leads the state in joint replacements, recognized as a Blue Distinction® Center. Beaufort Memorial in Beaufort is among only four SC hospitals with advanced certification for total hip and knee replacement, ensuring high patient safety. Conway Medical Center was the first in SC to offer partial knee replacement with the VELYS Robotic-Assisted Solution, while Lowcountry Orthopaedics in Charleston provides custom 3D-printed knees and outpatient robotic surgery.
For potential savings, consider Ambulatory Surgery Centers (ASCs) like those affiliated with Lowcountry Orthopaedics, offering same-day robotic-assisted knee replacement. Additionally, Greenville Health System Patewood Memorial Hospital and Pelham Medical Center were identified for best-value outcomes. Verify current pricing directly with providers.
Estimated Cost Breakdown in South Carolina
South Carolina falls slightly below the national average for knee replacement surgery costs. Here's the typical cost breakdown.
Facility Fee
OR time and hospital staffing
Most significant cost
Surgeon Fee
Expertise and experience level
Implants & Supplies
Post-Op Care
Recovery and aftercare
Anesthesia
Anesthesiologist or CRNA fee
Total Estimated Cost
South Carolina all-in range
Financing Options
Many South Carolina clinics partner with CareCredit or Alphaeon. A typical 24-month, 0% APR term on $32,725 looks like:
- Soft credit check — no hard pull
- Instant approval decisions
- HSA/FSA eligible for qualifying cases
Based on CMS Medicare data and regional price parities. Learn about our methodology →
Ranges adjusted for South Carolina's regional price parity (93.5). See the national percentage breakdown →
Facility Costs in South Carolina
South Carolina has both hospital and outpatient surgery center options for knee replacement surgery. Outpatient centers typically charge less due to lower overhead. Rates shown are negotiated amounts — what insurers actually pay, not inflated list prices.
| Facility | City | Negotiated Rate | Medicare | Volume |
|---|---|---|---|---|
| Prisma Health Patewood Hospital | Greenville | $11,594 | $9,989 | 1,005 |
| St Francis-Downtown | Greenville | $11,505 | $9,896 | 829 |
| Grand Strand Regional Medical Center | Myrtle Beach | $11,499 | $9,897 | 582 |
| Lexington Medical Center | West Columbia | $11,420 | $9,816 | 581 |
| Mcleod Regional Medical Center-Pee Dee | Florence | $11,295 | $9,691 | 489 |
| Spartanburg Medical Center | Spartanburg | $12,871 | $11,268 | 488 |
| Musc Medical Center | Charleston | $11,636 | $10,054 | 471 |
| Beaufort County Memorial Hospital | Beaufort | $12,171 | $10,566 | 470 |
| Mount Pleasant Hospital | Mount Pleasant | $12,066 | $10,459 | 436 |
| Mcleod Loris Hospital | Loris | $11,514 | $9,912 | 436 |
| Facility | City | Negotiated Rate | Medicare | Volume |
|---|---|---|---|---|
| Newberry County Memorial Hospital | Newberry | $16,468 | $14,487 | 154 |
| Roper Hospital | Charleston | $12,823 | $10,333 | 102 |
| Mount Pleasant Hospital | Mount Pleasant | $12,067 | $10,538 | 68 |
| St Francis-Downtown | Greenville | $13,197 | $10,803 | 67 |
| Musc Medical Center | Charleston | $20,269 | $15,371 | 44 |
| Prisma Health Patewood Hospital | Greenville | $13,327 | $10,459 | 43 |
| Mcleod Loris Hospital | Loris | $13,707 | $11,034 | 37 |
| Musc Health Columbia Medical Center Downtown | Columbia | $12,447 | $11,083 | 34 |
| East Cooper Medical Center | Mount Pleasant | $12,197 | $10,597 | 32 |
| Grand Strand Regional Medical Center | Myrtle Beach | $14,610 | $13,165 | 31 |
Knee Replacement Surgery Cost in Nearby States
South Carolina has the lowest knee replacement surgery costs in the region. Neighboring states all run higher — here's how they compare.
Expert Answers for South Carolina Patients
Local regulations, insurance nuance, and surgical standards specific to South Carolina.
Compare South Carolina with any other state
See national pricing, all 50 state comparisons, and detailed cost factors in the main knee replacement surgery cost guide.
View full knee replacement surgery guideWhat is the average price of knee replacement surgery in South Carolina?
Does insurance cover knee replacement surgery?
What's the recovery time for knee replacement surgery?
Are payment plans available for knee replacement surgery in South Carolina?
What should I look for in a South Carolina knee replacement surgery provider?
Does South Carolina Medicaid cover knee replacement surgery?
Is knee replacement surgery eligible for HSA/FSA funds?
How we calculate knee replacement surgery costs in South Carolina
Cost estimates combine procedure-specific pricing data with regional cost-of-living and provider-supply adjustments. Primary sources:
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Hospital pricing transparency files — CMS-required machine-readable data published by hospitals under the CMS Hospital Price Transparency rule (effective January 2021). Provides actual negotiated rates between hospitals and insurers.
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HCUP (Healthcare Cost & Utilization Project) — AHRQ's HCUP databases provide nationally-representative procedure cost data by state, payer, and patient demographics.
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Bureau of Labor Statistics — Healthcare Practitioner Occupational Wages — BLS OEWS data on surgeon, anesthesiologist, and surgical staff wages by state, used to model regional labor-cost differences in procedure pricing.
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BEA Regional Price Parities (RPP) — U.S. Bureau of Economic Analysis state-level price-level indices, used to adjust national procedure averages for South Carolina's cost-of-living relative to the national mean.
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FAIR Health Consumer Cost Lookup — the FAIR Health database aggregates billed and allowed amounts from over 36 billion claim records, providing a check on procedure-cost ranges by ZIP code.
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Medicare Provider Utilization & Payment Data — CMS public-use files on Medicare-allowed amounts and submitted charges by HCPCS/CPT code and state, used as a baseline for procedure-cost ranges.
Estimates are illustrative and reflect typical pricing ranges; actual costs depend on insurance coverage, surgical complexity, anesthesia type, hospital vs. ambulatory setting, and individual patient factors. Always confirm pricing directly with providers and your insurance carrier. See our methodology page for full calculation details.