Knee Replacement Surgery Cost in South Carolina (2026)
Modest savings vs. the US average · SC
Knee Replacement Surgery in South Carolina: What to Know
South Carolina offers diverse options for knee replacement. Prisma Health leads the state in joint replacements, recognized as a Blue Distinction® Center. Beaufort Memorial in Beaufort is among only four SC hospitals with advanced certification for total hip and knee replacement, ensuring high patient safety. Conway Medical Center was the first in SC to offer partial knee replacement with the VELYS Robotic-Assisted Solution, while Lowcountry Orthopaedics in Charleston provides custom 3D-printed knees and outpatient robotic surgery.
For potential savings, consider Ambulatory Surgery Centers (ASCs) like those affiliated with Lowcountry Orthopaedics, offering same-day robotic-assisted knee replacement. Additionally, Greenville Health System Patewood Memorial Hospital and Pelham Medical Center were identified for best-value outcomes. Verify current pricing directly with providers.
Estimated Cost Breakdown in South Carolina
South Carolina falls slightly below the national average for knee replacement surgery costs. Here's the typical cost breakdown.
| Component | Estimated Range |
|---|---|
| Facility Fee | $6,871 - $12,763 |
| Surgeon Fee | $6,871 - $12,763 |
| Implants Supplies | $3,435 - $6,381 |
| Post Op Care | $3,435 - $6,381 |
| Anesthesia | $2,291 - $4,254 |
| Total Estimated Cost | $18,700 – $46,750 |
Based on CMS Medicare data and regional price parities. Learn about our methodology →
Ranges adjusted for South Carolina's regional price parity (93.5). See the national percentage breakdown →
Facility Costs in South Carolina
South Carolina has both hospital and outpatient surgery center options for knee replacement surgery. Outpatient centers typically charge less due to lower overhead. Rates shown are negotiated amounts — what insurers actually pay, not inflated list prices.
| Facility | City | Negotiated Rate | Medicare Payment | Volume |
|---|---|---|---|---|
| Prisma Health Patewood Hospital | Greenville | $11,594 | $9,989 | 1,005 |
| St Francis-Downtown | Greenville | $11,505 | $9,896 | 829 |
| Grand Strand Regional Medical Center | Myrtle Beach | $11,499 | $9,897 | 582 |
| Lexington Medical Center | West Columbia | $11,420 | $9,816 | 581 |
| Mcleod Regional Medical Center-Pee Dee | Florence | $11,295 | $9,691 | 489 |
| Spartanburg Medical Center | Spartanburg | $12,871 | $11,268 | 488 |
| Musc Medical Center | Charleston | $11,636 | $10,054 | 471 |
| Beaufort County Memorial Hospital | Beaufort | $12,171 | $10,566 | 470 |
| Mount Pleasant Hospital | Mount Pleasant | $12,066 | $10,459 | 436 |
| Mcleod Loris Hospital | Loris | $11,514 | $9,912 | 436 |
| Facility | City | Negotiated Rate | Medicare Payment | Volume |
|---|---|---|---|---|
| Newberry County Memorial Hospital | Newberry | $16,468 | $14,487 | 154 |
| Roper Hospital | Charleston | $12,823 | $10,333 | 102 |
| Mount Pleasant Hospital | Mount Pleasant | $12,067 | $10,538 | 68 |
| St Francis-Downtown | Greenville | $13,197 | $10,803 | 67 |
| Musc Medical Center | Charleston | $20,269 | $15,371 | 44 |
| Prisma Health Patewood Hospital | Greenville | $13,327 | $10,459 | 43 |
| Mcleod Loris Hospital | Loris | $13,707 | $11,034 | 37 |
| Musc Health Columbia Medical Center Downtown | Columbia | $12,447 | $11,083 | 34 |
| East Cooper Medical Center | Mount Pleasant | $12,197 | $10,597 | 32 |
| Grand Strand Regional Medical Center | Myrtle Beach | $14,610 | $13,165 | 31 |
Knee Replacement Surgery Cost in Neighboring States
South Carolina has the lowest knee replacement surgery costs in the region. Neighboring states all run higher — here's how they compare.